Studying the Brain in Real Time

8232“Basic mechanisms in the brain have universal applications and are the road to medical discovery,” says Ralph Greenspan, PhD. He has spent his career studying how genes affect the brain and behavior of the fruit fly. This research has lead to a deeper understanding of mechanisms in the human brain. Hear about his current efforts to develop a full brain scale activity map and the technological and medical breakthroughs emerging from this work.

Studying the Brain in Real Time with Ralph Greenspan – On Our Mind

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Osteoporosis Update 2017

8232How do you know if you may have Osteoporosis? Should you take calcium or vitamin D supplements? What are the best exercises to keep your bones strong? Find out in this new Stein Institute for Research on Aging program that presents the latest information on osteoporosis.

Osteoporosis is a skeletal disorder that decreases bone density and strength and affects 1 in 3 women (1 in 5 men). Complications from related fractures cause more hospital time for women than many other diseases, including heart attack, stroke, and breast cancer.

According to Heather Hofflich, DO, FACE, Clinical Professor of Medicine, UC San Diego Health System, fractures related to osteoporosis are often a downward spiral, and it’s important to prevent them. If you’re over 50 and experience a fracture, it’s important to alert your primary care doctor to test for bone density to see if you are at risk.

Watch Osteoporosis Update 2017 to learn more about diagnosis, secondary causes, as well as treatment and prevention options.

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La Jolla Symphony & Chorus: The Lovers

8232When Dr. David Chase assumed leadership of the La Jolla Symphony Chorus in 1973, it consisted of 60 members. Over the succeeding years, Dr. Chase grew the chorus to 130 voices while expanding the group’s repertoire to include contemporary works as well as proven classics.

To mark his retirement after 44 years as Choral Director in June 2017, Dr. Chase assembled and conducted an eclectic program inspired by love and passion under the appropriate title, “The Lovers.” The first piece, the charming “Overture to Beatrice and Benedict,” is a concert staple from Hector Berlioz’s opera comique based on Shakespeare’s “Much Ado About Nothing.” Next on the bill is Arnold Schoenberg’s tone poem “Verklärte Nacht” (“Transfigured Night”), the composer’s interpretation of a German romantic poem. It is widely considered one of this modernist composer’s most accessible works. In the program’s final piece, “The Lovers,” American neo-Romantic composer Samuel Barber sets a cycle of poems by celebrated Chilean poet Pablo Neruda for baritone, mixed chorus, and full orchestra.

Taken as a whole the three pieces form a compelling examination of both the complexities of love and music’s ability to speak directly to the heart. Not coincidentally, the program also reflects David Chase’s passion for music and lifelong devotion to popularizing lesser-known works and is a fitting culmination to his tenure with La Jolla Symphony & Chorus. Dr. Chase will be ably succeeded, but he can never be replaced.

Watch La Jolla Symphony & Chorus: The Lovers

Aicardi-Goutieres: A Rare Disorder, A Unique Look into the Brain

8232Using brains-in-a-dish (cortical organoids), the Muotri Lab at UC San Diego has developed a new treatment for Aicardi-Goutieres syndrome. This study not only identified the underlying mechanisms that drive AGS but has also led to surprising revelations about neuroinflammation. Learn how they repurposed HIV antiretroviral drugs to rescue mutated cells and what this research means for studying other neurological conditions such as autism and schizophrenia.

Watch: Reconstructing the Brain in a Dish: Emergence of Neuroinflammation from Retrotransposons

Confronting Climate Change

8232Rosina Bierbaum, formerly of President Obama’s Council of Advisors on Science and Technology (PCAST) and an Adaptation Fellow at the World Bank, shows how climate change will affect all regions and sectors of the economy, and disproportionately affect the poorest people on the planet. Therefore, improving the resilience, adaptation, and preparedness of communities must be a high priority, equal to that of achieving deep greenhouse gas reductions and rapid development and deployment of innovative technologies, as well as altered planning and management strategies in the coming decades to achieve a sustainable world.

Watch Confronting Climate Change: Avoiding the Unmanageable, Managing the Unavoidable with Rosina Bierbaum – 2017 Keeling Memorial Lecture

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