Jennifer Doudna is a leader in the CRISPR revolution. This new technology is a gene editing tool that manipulates DNA within organisms. The editing process has a wide variety of applications including correcting genetic defects, treating and preventing the spread of diseases and improving crops.
Doudna, Professor of Biochemistry, Biophysics and Structural Biology at UC Berkeley, sat down to talk with Harry Kreisler about her life and how she came to be involved in this amazing discovery.
They also discuss how education and public advocacy can broaden insight into the ethical and policy dimensions of the biological revolution that is upon us.
Watch Unraveling CRISPR-Cas9 with Jennifer Doudna – Conversations with History
“All the best models are the ones that you can improve in complexity to get closer and closer to the reality.”
The idea of a brain in a dish may sound like science fiction to some but scientists are becoming more and more adept at creating cortical organoids in the lab. The organoids are models of what is happening in utero as the brain forms. Being able to study this kind of human development not only opens new insights into neurological conditions but raises ethical questions.
Alysson Muotri, director of the UC San Diego Stem Cell Program, gives a look at how his lab is using these organoids to model specific conditions, treat disease, and explore fundamental brain mechanisms. Learn what the limitations, future projections, and ethical concerns are surrounding this exciting science.
Watch Re-constructing Brains in the Lab to Revolutionize Neuroscience – Exploring Ethics