Svante Pääbo once said, “We are all Africans, either living in Africa or in recent exile from Africa.”
It is now abundantly clear that Africa was the “cradle of humanity,” with multiple waves of hominins arising on that continent and spreading across the old world, eventually being effectively displaced by our own species, which also arose in Africa.
Given these facts, it is not surprising that the strong emphasis of anthropogeny is on the continent of Africa with wide-ranging studies including genetic, paleontological, archeological, primatological, climatological, sociocultural and more.
This CARTA symposium focuses on the contributions of scientists and scholars of anthropogeny who live and work in Africa.
Browse more programs in Anthropogeny: The Perspective from Africa.
Mosquitos are the deadliest animal on Earth. They spread diseases like yellow fever, chikungunya, West Nile virus and malaria. Malaria alone killed 435,000 people and infected another 219 million in 2017 according to the World Health Organization. There are widespread efforts to combat mosquito-borne illnesses, including revolutionary new gene editing techniques.
Ethan Bier and Valentino Gantz, biologists at UC San Diego, have been researching gene drives – systems that allow scientists to quickly push genes through entire populations. Typically, genetic information from each parent is combined and passed down to their children. Think back to Punnett squares from high school biology. If one parent has blonde hair and the other has brown hair, the brunette would have to carry a recessive blonde gene for any of their children to be blonde. But, gene drives change that. Gantz and Bier came up with a way to use the CRISPR gene-editing technique to insert self-editing genes into mosquitos, so preferred traits are always passed down. Their research shows these traits can take over entire populations within 10 generations, one to two years for mosquitos.
In a recent talk at UC San Diego Extension’s Osher Lifelong Learning Institute, Bier dove into the details of exactly how gene drives work, and their many potential applications.
Watch — Engineering Mosquitos to Fight Malaria with Ethan Bier — Osher UC San Diego